Secure Cloud-Native Infrastructure: DevSecOps, IaC Security, and Compliance-Driven Enterprise Systems explores the evolving landscape of modern infrastructure security in cloud-native environments. The book provides a comprehensive understanding of DevSecOps engineering, Infrastructure-as-Code (IaC) security, CI/CD pipeline protection, zero-trust architectures, compliance automation, observability, and resilience engineering. It explains how organizations can build scalable, secure, and adaptive enterprise systems capable of withstanding emerging cyber threats across multi-cloud and distributed ecosystems. A major highlight of the book is the introduction of the Secure Cloud-Native Infrastructure Framework (SCNIF), a unified model designed to integrate governance, observability, intelligent threat management, and resilience into modern infrastructures. Written with a balance of theoretical depth and practical relevance, this book serves as a valuable resource for cybersecurity professionals, cloud architects, DevOps engineers, researchers, and enterprise leaders seeking to secure digital transformation initiatives in increasingly complex technological environments.