This textbook presents the principles, processes, and methodologies integral to pharmacovigilance. The chapters are structured to offer clarity on core concepts, including adverse event reporting, risk assessment, regulatory requirements, and signal detection, as well as emerging trends such as digital pharmacovigilance and the role of artificial intelligence. Each chapter emphasizes the practical implementation of pharmacovigilance practices, underpinned by real-world case studies and examples from diverse healthcare settings. The aim of A Textbook of Pharmacovigilance is not only to impart knowledge but also to inspire a culture of safety among future healthcare professionals. In addition to providing detailed insights into the regulatory frameworks and compliance standards set by global authorities, this text emphasizes the ethical responsibility every healthcare professional hold in the detection and reporting of ADRs.